Have you ever felt left out, isolated, rejected, and/or frustrated that your parents, your siblings, or even your classmates do not seem to understand you? If so, you are not alone. In the 1980s, scientific reports indicated that 2 out of 10 people felt socially isolated at any given time. Two recent national surveys indicate that this number has now doubled. Children and adolescents are not spared from loneliness. As many as 80% of those under the age of 18 years report feelings of loneliness at some point [1]. As an illustrative case, a survey conducted from April 2008 to March 2009 by the National Society for the Prevention of Cruelty to Children (NSPCC) in the United Kingdom reported that approximately 10,000 children contacted their help line regarding loneliness-related issues. Figure 1 shows that most of these phone calls came from 16-year-old children [2]. Given the rise in reports of people feeling lonely, a growing number of research laboratories have begun to investigate the causes and consequences of loneliness. In this article, we review the literature in this field and suggest a few actions that one might take when feeling lonely.